JAK-IN-18
JAK-IN-18 is a potent inhibitor of JAK. JAK-IN-18 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2018204238A1, compound 1) [1].
Product Specifications
CAS Number
2247925-32-0
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak-in-18.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(C2=CC(F)=C(O)C=C2CC)=CC3=C1C(C(N4)=NC5=C4CN(C(CN6CCOCC6)=O)CC5)=NN3
Molecular Formula
C27H28F2N6O3
Molecular Weight
522.55
References & Citations
[1]Paul R. Fatheree, et al. Fused imidazo-piperidine jak inhibitor compound. Patent WO2018204238A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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