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HBV-IN-16

HBV-IN-16 is a potent inhibitor of covalently closed circular DNA (cccDNA) . cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-16 is a quinoline derivative. HBV-IN-16 has the potential for the research of HBV infection (extracted from patent WO2019121357A1, compound 1) [1].

Product Specifications

CAS Number

[2355225-38-4]

UNSPSC

12352005

Target

DNA/RNA Synthesis; HBV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hbv-in-16.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=CC2=C1N=C(C3=CC=C(C=C3)OCCO[C@H]4C[C@H](C4)C(O)=O)C=C2

Molecular Formula

C22H20ClNO4

Molecular Weight

397.85

References & Citations

[1] Song Feng, et al. Novel quinoline compounds for the treatment and prophylaxis of hepatitis b virus disease. Patent WO2019121357A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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