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EGFR-IN-30

EGFR-IN-30 is a potent EGFR inhibitor with IC50s of 1-10 nM, [1].

Product Specifications

CAS Number

2726463-68-7

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-30.html

Solubility

10 mM in DMSO

Smiles

O=P(C)(C)C1=C(NC2=NC(NC3=C(OC)C=C4N(C(C)C)CCC5=C(C=NN5C)C4=C3)=NC=C2Br)C=CC=C1

Molecular Formula

C28H33BrN7O2P

Molecular Weight

610.49

References & Citations

[1]Shansong Zheng, et al. Tricyclic compounds as EGFR inhibitors. WO2021208918A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EGFR/ErbB1/HER1

Frequently Asked Questions

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