CSF1R-IN-5
CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-5 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-5 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 11) [1].
Product Specifications
CAS Number
2716184-93-7
UNSPSC
12352005
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csf1r-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN=C2N(CCC2)C1=O)NC3=NC=C(C=C3)OC4=CC=NC(C5=CN(C)N=C5)=C4
Molecular Formula
C22H19N7O3
Molecular Weight
429.43
References & Citations
[1] Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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