CSF1R-IN-4
Product Specifications
UNSPSC Description
CSF1R-IN-4 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-4 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 104)[1].
Target Antigen
c-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csf1r-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CN(C2CC2)C1=O)NC3=NC=C(OC4=CC(C5=CN(C)N=C5)=NC=C4)C=C3
Molecular Weight
428.44
References & Citations
[1]Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144040/CSF1R-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144040/
Clinical Information
No Development Reported
CAS Number
2716185-86-1
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