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GLP-1R agonist 1

GLP-1R agonist 1 is a potent agonist of GLP-1R. GLP-1R agonist 1 is a thickened imidazole derivative compound. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 1 has the potential for the research of diabetes (extracted from patent WO2021197464A1, compound 4) [1].

Product Specifications

CAS Number

[2711019-49-5]

UNSPSC

12352005

Target

GCGR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1r-agonist-1.html

Solubility

10 mM in DMSO

Smiles

C[C@@]1(C2=C(C=C(C=C2)Cl)F)OC3=C(C4=CCN(CC(N(C5=C6)C[C@@H]7CCO7)=NC5=CC=C6C(O)=O)CC4)C=CC=C3O1

Molecular Formula

C32H29ClFN3O5

Molecular Weight

590.04

References & Citations

[1]Fanglong Yang, et al. Thickened imidazole derivatives, methods of their preparation and their application in medicine. Patent WO2021197464A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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