DPPE-PEG750

DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

Product Specifications

CAS Number

[474922-84-4]

Product Name Alternative

16:0 PEG750 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (polyethylene glycol) -750] (ammonium)

UNSPSC

12352200

Target

Biochemical Assay Reagents; Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/16-0-peg750-pe.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)=O)OCCOC.N.[n]

Molecular Formula

(C2H4O) nC39H76NO10P.H3N

Molecular Weight

750 (Average)

References & Citations

[1]Xiao H, et al. Regulation of microglia polarization via mannose receptor-mediated delivery of siRNA by ligand-functionalized DoGo LNP. RSC Adv. 2021 Oct 4;11 (52) :32549-32558.|[2]Sommonte F, et al. In-House Innovative "Diamond Shaped" 3D Printed Microfluidic Devices for Lysozyme-Loaded Liposomes. Pharmaceutics. 2022 Nov 16;14 (11) :2484.