Cysteinylglycine

Cysteinylglycine is a dipeptide produced by the decomposition of extracellular glutathione catalyzed by γ-glutamyl transpeptidase. Cysteinylglycine is a highly reactive metabolite. Cysteinylglycine is currently mainly used in neurodegenerative diseases and breast cancer research[1][2][3][4].

Product Specifications

CAS Number

[19246-18-5]

Product Name Alternative

L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH

UNSPSC

12352209

Hazard Statement

H315, H319, H372, H413

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cysteinylglycine.html

Purity

99.96

Solubility

H2O : 175 mg/mL (ultrasonic)

Smiles

O=C(O)CNC([C@H](CS)N)=O

Molecular Formula

C5H10N2O3S

Molecular Weight

178.21

Precautions

H315, H319, H372, H413

References & Citations

[1]Houghton SC, et al. Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folicacid fortification in the United States. Int J Cancer. 2019 Apr 15;144 (8) :1929-1940.|[2]Steele M L, et al. Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. Redox biology, 2013, 1 (1) : 441-445.|[3]Mansoor MA, et al. Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma. Anal Biochem. 1992 Feb 1;200 (2) :218-29.|[4]Lin J, et al. Plasma cysteinylglycine levels and breast cancer risk in women. Cancer Res. 2007 Dec 1;67 (23) :11123-7.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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