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HER2-IN-7

HER2-IN-7 is a potent inhibitor of HER2. Deregulation of ErbB family signalling modulates proliferation, invasion, metastasis, angiogenesis, and tumour cell survival. HER2-IN-7 has the potential for the research of diseases associated ErbBs (especially HER2), including cancer (extracted from patent WO2019214634A1, compound 23) [1].

Product Specifications

CAS Number

2387574-01-6

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/her2-in-7.html

Solubility

10 mM in DMSO

Smiles

COC1=C(OC2C(F)(F)CN(C)CC2)C3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5F)C(C)=C4)N=CN=C3C=C1

Molecular Formula

C28H26F3N7O3

Molecular Weight

565.55

References & Citations

[1]Zhengtao LI, et al. Erbb receptor inhibitors. Patent WO2019214634A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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