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HPK1-IN-30

HPK1-IN-30 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1) . MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-30 has the potential for the research of cancer diseases (extracted from patent WO2021175271A1, compound 3) [1].

Product Specifications

CAS Number

[2700292-56-2]

UNSPSC

12352005

Target

MAP4K

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hpk1-in-30.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC2=C(C=C1C3=C(C)C=CC=C3F)C(C4=CN(C5CCNCC5)N=C4)=CN=C2N

Molecular Formula

C25H23FN6

Molecular Weight

426.49

References & Citations

[1]Jiang Lei, et al. Novel hpk1 inhibitor and preparation method and application thereof. Patent WO2021175271A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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