RIPK1-IN-8
RIPK1-IN-8 (example 16), an aminoimidazopyridine, is a potent and selective RIPK1 inhibitor with an IC50 of 4 nM. RIPK1-IN-8 has the potential for inflammatory diseases research[1].
Product Specifications
CAS Number
[2319663-07-3]
UNSPSC
12352005
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ripk1-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C2=NN3C(C=C2)=NC(NC(C)=O)=C3)=C(C)N=C1)NCC4=CC(F)=CC(F)=C4OCC5CC5
Molecular Formula
C26H24F2N6O3
Molecular Weight
506.50
References & Citations
[1]Michael E. Mertzman, et al. Aminoimidazopyridines as kinase inhibitors. WO2019089442A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RIPK1
Curated Selection
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