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JAK3/BTK-IN-2

JAK3/BTK-IN-2 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-2 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147952A1, compound 004) [1]

Product Specifications

CAS Number

2674036-93-0

UNSPSC

12352005

Target

Btk; JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/jak3-btk-in-2.html

Solubility

10 mM in DMSO

Smiles

C=CC(N1C[C@H](NC2=C3C(NC=C3C4CC4)=NC(NC5=CN(C6CCOCC6)N=C5)=N2)CCC1)=O

Molecular Formula

C25H32N8O2

Molecular Weight

476.57

References & Citations

[1]Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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