JAK3/BTK-IN-1
JAK3/BTK-IN-1 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-1 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147952A1, compound 002) [1].
Product Specifications
CAS Number
2674036-91-8
UNSPSC
12352005
Target
Btk; JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak3-btk-in-1.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1C[C@H](NC2=C3C(NC=C3C4=CC=CC=C4)=NC(NC5=CN(CC)N=C5)=N2)CCC1)=O
Molecular Formula
C25H28N8O
Molecular Weight
456.54
References & Citations
[1]Guobao Zhang, et al. Pyrimidopyrroles. Patent WO2021147952A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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