Antibiotic A-33853

Antibiotic A-338533, an antibiotic, can be isolated from Streptomyces strain. Antibiotic A-338533 has anti-bacterial activity against Staphylococcus aureus, Mycoplasma gallisepticum with MIC values of 2 μg/mL and ≤1.56 μg/mL, respectively[1].

Product Specifications

CAS Number

[80148-45-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibiotic-a-33853.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C2N=C(C3=CC=CC(O)=C3NC(C4=NC=CC=C4O)=O)OC2=CC=C1)O

Molecular Formula

C20H13N3O6

Molecular Weight

391.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]In Pursuit of Natural Product Leads: Synthesis and Biological Evaluation of 2-[3-hydroxy-2-[ (3-hydroxypyridine-2-carbonyl) amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and Its Analogues: Discovery of N- (2-Benzoxazol-2-ylphenyl) benzamides as Novel Antileishmanial Chemotypes J. Med. Chem., 2008, 51 (23), pp 7344-7347|[2]Michel KH, et al. The discovery, fermentation, isolation, and structure of antibiotic A33853 and its tetraacetyl derivative. J Antibiot (Tokyo) . 1984 May;37 (5) :441-5.