QW24
QW24 exerts potent anti-tumor activity by down-regulating BMI-1 and is used as an effective therapeutic agent for clinical colorectal cancer research.
Product Specifications
CAS Number
2416312-06-4
UNSPSC
12352005
Target
Autophagy; BMI1
Type
Reference compound
Related Pathways
Autophagy; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qw24.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C=C1CCC2C3(C)C)=C(OC)C=C1[C@@]2(C)C=C(C#N)C3=O)NC4=CC=C(OC)C=C4
Molecular Formula
C27H28N2O4
Molecular Weight
444.52
References & Citations
[1]Wang J, et al. A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer. J Exp Clin Cancer Res. 2019 Oct 22;38 (1) :422.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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