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QW24

QW24 exerts potent anti-tumor activity by down-regulating BMI-1 and is used as an effective therapeutic agent for clinical colorectal cancer research.

Product Specifications

CAS Number

2416312-06-4

UNSPSC

12352005

Target

Autophagy; BMI1

Type

Reference compound

Related Pathways

Autophagy; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/qw24.html

Solubility

10 mM in DMSO

Smiles

O=C(C(C=C1CCC2C3(C)C)=C(OC)C=C1[C@@]2(C)C=C(C#N)C3=O)NC4=CC=C(OC)C=C4

Molecular Formula

C27H28N2O4

Molecular Weight

444.52

References & Citations

[1]Wang J, et al. A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer. J Exp Clin Cancer Res. 2019 Oct 22;38 (1) :422.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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