WW437
WW437 is a histone deacetylase (HDAC) inhibitor with potent anti-breast cancer ability in vitro and in vivo.
Product Specifications
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ww437.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)N(C(CCCCCC(NO)=O)=O)CC2=CN(N=N2)C3=CC=CC=C3
Molecular Formula
C23H27N5O4
Molecular Weight
437.49
References & Citations
[1]Zhang T, et al. Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer. EBioMedicine. 2018 May;31:276-286.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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