PhotoCORM-1

PhotoCORM-1 (compound 8) is a combinatorial carbon monoxide releasing molecule (CORM) . photoCORM-1 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-1 has anti-tumor antivity[1].

Product Specifications

CAS Number

[2892235-56-0]

UNSPSC

12352005

Target

Photosensitizer

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/photocorm-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC2=C(N(C3=CC=C(C=C32)C(O4)=COC4=O)CC)C=C1)COC(CCCC5=CC=C(C=C5)N(CCCl)CCCl)=O

Molecular Formula

C33H32Cl2N2O6

Molecular Weight

623.52

References & Citations

[1]Venkatesh Y, et al. One- and Two-Photon Uncaging of Carbon Monoxide (CO) with Real-Time Monitoring: On-Demand Carbazole-Based Dual CO-Releasing Platform to Test over Single and Combinatorial Approaches for the Efficient Regression of Orthotopic Murine Melanoma In Vivo. J Med Chem. 2022;65 (3) :1822-1834.|[2]Venkatesh Y, et al. One- and Two-Photon Uncaging of Carbon Monoxide (CO) with Real-Time Monitoring: On-Demand Carbazole-Based Dual CO-Releasing Platform to Test over Single and Combinatorial Approaches for the Efficient Regression of Orthotopic Murine Melanoma In Vivo. J Med Chem. 2022 Feb 10;65 (3) :1822-1834.. . . .