THR-β agonist 2
THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021121210A1, compound 3) [1].
Product Specifications
CAS Number
[2440027-77-8]
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/thr-β-agonist-2.html
Purity
99.31
Solubility
DMSO : 350 mg/mL (ultrasonic)
Smiles
N#CC1=NN(C2=CC(Cl)=C(OC3=NNC(C4=C3C=CC=C4)=O)C(Cl)=C2)C(NC1=O)=O
Molecular Formula
C18H8Cl2N6O4
Molecular Weight
443.20
References & Citations
[1]Fanglong Yang, et al. Heterocyclic derivatives, their preparation methods and their application in medicine. Patent WO2021121210A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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