THR-β agonist 2

THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021121210A1, compound 3) [1].

Product Specifications

CAS Number

[2440027-77-8]

UNSPSC

12352005

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/thr-β-agonist-2.html

Purity

99.31

Solubility

DMSO : 350 mg/mL (ultrasonic)

Smiles

N#CC1=NN(C2=CC(Cl)=C(OC3=NNC(C4=C3C=CC=C4)=O)C(Cl)=C2)C(NC1=O)=O

Molecular Formula

C18H8Cl2N6O4

Molecular Weight

443.20

References & Citations

[1]Fanglong Yang, et al. Heterocyclic derivatives, their preparation methods and their application in medicine. Patent WO2021121210A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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