KRAS G12D inhibitor 12
KRAS G12D inhibitor 12 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 12 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 134) [1].
Product Specifications
CAS Number
2648552-54-7
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-12.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CN1)N2CCN3C4=NC=NC5=C4C(OCC[C@@H]3C2)=C(C(C6=C(C=CC=C6O)F)=C5)Cl
Molecular Formula
C23H21ClFN5O3
Molecular Weight
469.90
References & Citations
[1]Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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