KRAS G12D inhibitor 11
KRAS G12D inhibitor 11 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 11 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 52) [1].
Product Specifications
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-11.html
Solubility
10 mM in DMSO
Smiles
CN(CCC1)[C@@H]1COC2=NC(N3CCC(CC3)B(O)O)=C4C(CN(C5=CC=CC6=C5C(C)=CC=C6)CC4)=N2
Molecular Formula
C29H38BN5O3
Molecular Weight
515.45
References & Citations
[1]Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143604/KRAS-G12D-inhibitor-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143604/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[2648551-72-6]
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