KRAS G12D inhibitor 8
KRAS G12D inhibitor 8 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 8 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021107160A1, compound 2) [1].
Product Specifications
CAS Number
2648221-05-8
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-8.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C=CC=C2Br)=C2C(N3CC4=NC(OCC5(CC5)CN6C[C@@H](CC6)F)=NC(N7CC8NC(CC8)C7)=C4CC3)=C1
Molecular Formula
C32H38BrFN6O2
Molecular Weight
637.59
References & Citations
[1]Yuichi Kawai, et al. A compound having inhibitory activity against kras g12d mutation. Patent WO2021107160A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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