KRAS G12C inhibitor 42
KRAS G12C inhibitor 42 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 42 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2020146613A1, compound 10) [1].
Product Specifications
CAS Number
[2454488-02-7]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-42.html
Solubility
10 mM in DMSO
Smiles
N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C(C=NC(C3=C4C(C)=CC=CC4=CC=C3)=C5F)C5=NC(OC[C@H]6N(C)CCC6)=N2)C1
Molecular Formula
C33H34FN7O2
Molecular Weight
579.67
References & Citations
[1]Matthew Arnold Marx, et al. Kras g12c inhibitors. Patent WO2020146613A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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