KRAS G12C inhibitor 42
Product Specifications
UNSPSC Description
KRAS G12C inhibitor 42 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 42 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2020146613A1, compound 10)[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-42.html
Solubility
10 mM in DMSO
Smiles
N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C(C=NC(C3=C4C(C)=CC=CC4=CC=C3)=C5F)C5=NC(OC[C@H]6N(C)CCC6)=N2)C1
Molecular Weight
579.67
References & Citations
[1]Matthew Arnold Marx, et al. Kras g12c inhibitors. Patent WO2020146613A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143598/KRAS-G12C-inhibitor-42-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143598/
Clinical Information
No Development Reported
CAS Number
2454488-02-7
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