KRAS G12C inhibitor 41
KRAS G12C inhibitor 41 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 41 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129824A1, compound 121) [1].
Product Specifications
CAS Number
[2660014-65-1]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-41.html
Solubility
10 mM in DMSO
Smiles
CN1CCC[C@H]1COC2=NC(N3C[C@@H](N(CC3)C(C(C4=CN=CN=C4)=C)=O)CC#N)=C5C(CN(C6=CC=CC7=C6C(Cl)=C(F)C=C7)CC5)=N2
Molecular Formula
C36H37ClFN9O2
Molecular Weight
682.19
References & Citations
[1]Yuli Xie, et al. Novel K-Ras G12C inhibitor. Patent WO2021129824A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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