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KRAS G12C inhibitor 40

KRAS G12C inhibitor 40 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 40 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021129824A1, compound 70) [1].

Product Specifications

CAS Number

[2660014-14-0]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12c-inhibitor-40.html

Solubility

10 mM in DMSO

Smiles

N#CC[C@@H]1N(C(/C=C/N2N=CN=C2)=O)CCN(C3=C4C(CN(C5=C6C(Cl)=C(F)C=CC6=CC=C5)CC4)=NC(OC[C@H]7N(C)CCC7)=N3)C1

Molecular Formula

C34H36ClFN10O2

Molecular Weight

671.17

References & Citations

[1]Yuli Xie, et al. Novel K-Ras G12C inhibitor. Patent WO2021129824A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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