KRAS G12C inhibitor 37
KRAS G12C inhibitor 37 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 37 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2018143315A1, compound 65) [1].
Product Specifications
CAS Number
2241720-04-5
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-37.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CC2(C1)CCN(CC2)C3=NC(N4CC(C4)N(C)C)=NC5=C(C(C6=C7C=NNC7=CC=C6C)=C(C=C35)C=C)OCC(F)(F)F)=O
Molecular Formula
C35H39F3N8O2
Molecular Weight
660.73
References & Citations
[1]Quinazoline compound. Patent WO2018143315A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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