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P2X3 antagonist 37

P2X3 antagonist 37 is a potent P2X3 receptor antagonist with an IC50 of 32.45 nM for hP2X3 (WO2021115225A1, example 68) [1].

Product Specifications

CAS Number

2649318-40-9

UNSPSC

12352005

Target

P2X Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/p2x3-antagonist-37.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NC=C(F)C=C1)CN2C3=CC(C#N)=NN3C4=NC(C(F)(F)F)=CC=C4C2=O

Molecular Formula

C18H9F4N7O2

Molecular Weight

431.30

References & Citations

[1]Pyrazole-containing polycyclic derivative inhibitor, preparation method therefor and application thereof. WO2021115225A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

P2X3 Receptor

Frequently Asked Questions

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