P2X3 antagonist 37
P2X3 antagonist 37 is a potent P2X3 receptor antagonist with an IC50 of 32.45 nM for hP2X3 (WO2021115225A1, example 68) [1].
Product Specifications
CAS Number
2649318-40-9
UNSPSC
12352005
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/p2x3-antagonist-37.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC=C(F)C=C1)CN2C3=CC(C#N)=NN3C4=NC(C(F)(F)F)=CC=C4C2=O
Molecular Formula
C18H9F4N7O2
Molecular Weight
431.30
References & Citations
[1]Pyrazole-containing polycyclic derivative inhibitor, preparation method therefor and application thereof. WO2021115225A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X3 Receptor
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