NLRP3 antagonist 1
NLRP3 antagonist 1 is a potent antagonist of NLRP3. NLRP3 is mainly expressed in macrophages and neutrophils and is involved in the body's intrinsic immunity against pathogenic infections and stress injury. NLRP3 antagonist 1 has the potential for the research of cancer disease (extracted from patent WO2021114691A1, compound 3) [1].
Product Specifications
CAS Number
[2454017-83-3]
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nlrp3-antagonist-1.html
Concentration
10mM
Purity
98.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](NC2=C3C=CC(C4=NNC=C4)=CC3=NC(N)=N2)CCC1
Molecular Formula
C16H18N6O
Molecular Weight
310.35
References & Citations
[1]Zejin You, et al. Nitrogen-containing and cyclic compounds, their preparation methods and uses. Patent WO2021114691A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Available Sizes
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