TP-16
TP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.
Product Specifications
CAS Number
[2332972-26-4]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tp-16.html
Solubility
10 mM in DMSO
Smiles
C[C@@H](C1=CC=C(C=C1)C(O)=O)NC(C2=C(CC3=CC=C(C=C3)F)SC4=C2CCOC4)=O
Molecular Formula
C24H22FNO4S
Molecular Weight
439.50
References & Citations
[1]Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13 (1) :e12798.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP
Available Sizes
Curated Selection
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