TP-16

TP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.

Product Specifications

CAS Number

[2332972-26-4]

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tp-16.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](C1=CC=C(C=C1)C(O)=O)NC(C2=C(CC3=CC=C(C=C3)F)SC4=C2CCOC4)=O

Molecular Formula

C24H22FNO4S

Molecular Weight

439.50

References & Citations

[1]Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13 (1) :e12798.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Available Sizes

Curated Selection

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