844-TFM
Product Specifications
UNSPSC Description
844-TFM is a NBTI (novel bacterial topoisomerase inhibitor) DNA gyrase inhibitor, with an IC50 of 1.5 μM. 844-TFM exhibits bactericidal properties against M. abscessus[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/844-tfm.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C2N=CC=C(C2=N1)NC(C3CCN(CC3)CCC4=CC=C(C=C4)C(F)(F)F)=O
Molecular Weight
458.48
References & Citations
[1]Beuchel A, et, al. Structure-Activity Relationship of Anti- Mycobacterium abscessus Piperidine-4-carboxamides, a New Class of NBTI DNA Gyrase Inhibitors. ACS Med Chem Lett. 2022 Feb 28;13(3):417-427.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143484/844-TFM-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143484/
Clinical Information
No Development Reported
CAS Number
2767443-97-8
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