POP-IN-3
Y-29794 (Compound 2) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 0.95 nM. Y-29794 can be used for studying neurodegenerative diseases and cancer[1].
Product Specifications
CAS Number
2554621-98-4
UNSPSC
12352005
Target
Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pop-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C(C)C)N=C1SCCCCCCCN(C)C)C2=CC=CS2
Molecular Formula
C22H32N2OS2
Molecular Weight
404.63
References & Citations
[1]Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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