NPP1-IN-1
NPP1-IN-1 is a potent NPP inhibitor with IC50s of 0.15 μM and 40 μM for NPP1 and NPP3, respectively[1].
Product Specifications
CAS Number
[2493063-65-1]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/npp1-in-1.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC1=CC=CC=C1C2=NC(C3=CC=C(C4=C5C=CC=CC5=CC=C4)C=C3)=CO2
Molecular Formula
C27H21NO2
Molecular Weight
391.46
References & Citations
[1]Ahmad H, Ullah S, Rahman F, et al. Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors. Eur J Med Chem. 2020;208:112759.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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