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CK2 inhibitor 3

CK2 inhibitor 3 is a potent CK2 inhibitor with IC50 value of 280 nM. CK2 inhibitor 3 inhibits endocellular CK2, significantly affects viability of tumour cells and shows remarkable selectivity on a panel of 320 kinases[1].

Product Specifications

UNSPSC

12352005

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ck2-inhibitor-3.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(/C=C(C(NC2=NN=C(S2)Br)=O)\C#N)=CC=C1O

Molecular Formula

C13H9BrN4O3S

Molecular Weight

381.20

References & Citations

[1]Dalle Vedove A, Zonta F, Zanforlin E, et al. A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur J Med Chem. 2020;195:112267.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CK2

Frequently Asked Questions

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