Germination-IN-2
Germination-IN-2 (compound 15) is a potent germination inhibitor with an IC50 of 1.3 µM. Germination-IN-2 shows anti-germination activity with 3% germination rate[1].
Product Specifications
CAS Number
[89846-43-5]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/germination-in-2.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NC3=CC=CC=C3)=O)([H])[C@@]4([H])[C@@](C[C@@H]1O)([H])[C@@]5([C@](C[C@@H](CC5)O)([H])CC4)C
Molecular Formula
C30H45NO3
Molecular Weight
467.68
References & Citations
[1]Sharma SK, et al. Studies on the Importance of the 7α-, and 12α- hydroxyl groups of N-Aryl-3α,7α,12α-trihydroxy-5β-cholan-24-amides on their Antigermination Activity Against a Hypervirulent Strain of Clostridioides (Clostridium) difficile. Bioorg Med Chem. 2021 Dec 15;52:116503.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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