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(S) -MALT1-IN-5

(S) -MALT1-IN-5 is a potent inhibitor of MALT1 protease. (S) -MALT1-IN-5 inhibits the activity of MALT1 is expected to be able to correct the enhancement of MALT1 activity due to abnormality of T cell receptor signal or B cell receptor signal, and cancer or inflammatory disease caused by MALT1 activity is expected. (S) -MALT1-IN-5 has the potential for the research of MALT1-related diseases (extracted from patent WO2020111087A1, compound 1) [1].

Product Specifications

CAS Number

[2434602-25-0]

UNSPSC

12352005

Target

MALT1

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/s-malt1-in-5.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C([C@@H](OC)C)C2=NC(C)=CN2N=C1)NC3=CC(Cl)=C(OC(F)F)N=C3

Molecular Formula

C17H17ClF2N6O3

Molecular Weight

426.81

References & Citations

[1]Heterocyclic compound. Patent WO2020111087A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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