(S) -MALT1-IN-5
(S) -MALT1-IN-5 is a potent inhibitor of MALT1 protease. (S) -MALT1-IN-5 inhibits the activity of MALT1 is expected to be able to correct the enhancement of MALT1 activity due to abnormality of T cell receptor signal or B cell receptor signal, and cancer or inflammatory disease caused by MALT1 activity is expected. (S) -MALT1-IN-5 has the potential for the research of MALT1-related diseases (extracted from patent WO2020111087A1, compound 1) [1].
Product Specifications
CAS Number
[2434602-25-0]
UNSPSC
12352005
Target
MALT1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-malt1-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C([C@@H](OC)C)C2=NC(C)=CN2N=C1)NC3=CC(Cl)=C(OC(F)F)N=C3
Molecular Formula
C17H17ClF2N6O3
Molecular Weight
426.81
References & Citations
[1]Heterocyclic compound. Patent WO2020111087A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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