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MALT1-IN-3

MALT1-IN-3 (compound 122) is a potent MALT1 protease inhibitor, with an IC50 of 0.06 μM. MALT1-IN-3 has IC50 of 0.14 and 0.13 μM for human IL6/IL10 in OCI-LY3 cells, respectively[1].

Product Specifications

CAS Number

2504229-63-2

UNSPSC

12352005

Target

MALT1

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/malt1-in-3.html

Solubility

10 mM in DMSO

Smiles

CO[C@@H](C1CC1)C2=C(C#N)C(C)=NC=C2NC(NC3=CN=C(N4N=CC=N4)C(C(F)(F)F)=C3)=O

Molecular Formula

C21H19F3N8O2

Molecular Weight

472.42

References & Citations

[1]Johannes Wilhelmus J Thuring, et al. Pyridine rings containing derivatives as malt1 inhibitors. WO2020208222A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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