Antimalarial agent 10
Product Specifications
UNSPSC Description
Antimalarial agent 10 (Compound 17b) is an aminoalcohol quinoline compound. Antimalarial agent 10 is an antimalarial agent with IC50 values of 14.9 nM and 11.0 nM against respectively Pf3D7 and PfW2 and a selectivity index higher than 770 whatever the cell line is[1].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-10.html
Solubility
10 mM in DMSO
Smiles
FC(F)(C1=CC=CC2=C1N=C(C(F)(F)F)C=C2[C@H](O)CN[C@H](COC)CC3=CC=CC=C3)F
Molecular Weight
472.42
References & Citations
[1]Dassonville-Klimpt A, et al. Design, synthesis, and characterization of novel aminoalcohol quinolines with strong in vitro antimalarial activity. Eur J Med Chem. 2022;228:113981.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143409/Antimalarial-agent-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143409/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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