Cdc7-IN-8
Cdc7-IN-8 is a potent inhibitor of Cdc7. Cdc7 is a serine/threonine kinase which activates MCM promotion by phosphorylating the microchromosome maintenance protein (MCM protein), an important element of the DNA replication initiator. Cdc7-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021032170A1, compound 1-1/1-2) [1].
Product Specifications
CAS Number
2606780-38-3
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc7-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C3=C(O2)C4=CNN=C4CCC3)N=C(N1)[C@@H]5CC6CCN5CC6
Molecular Formula
C19H21N5O2
Molecular Weight
351.40
References & Citations
[1]Lun Lu, et al. Tetracyclic compound used as cdc7 inhibitor. Patent WO2021032170A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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