SB 271046
Product Specifications
UNSPSC Description
SB 271046 is a potent, selective and orally active 5-HT6 receptor antagonist with a pKi of 8.92-9.09. SB 271046 show >200-fold selective for the 5-HT6 receptor over other receptors, binding sites and ion channels. SB 271046 has anticonvulsant activity[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-271046.html
Solubility
10 mM in DMSO
Smiles
O=S(NC1=CC=C(C(N2CCNCC2)=C1)OC)(C3=C(C)C4=C(C=CC(Cl)=C4)S3)=O
Molecular Weight
451.99
References & Citations
[1]C Routledge, et al. Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonist. Br J Pharmacol. 2000 Aug;130(7):1606-12.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14336/SB-271046-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14336/
Clinical Information
No Development Reported
CAS Number
209481-20-9
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