BRD4-BD1-IN-2
BRD4-BD1-IN-2 is a selective BRD4-BD1 inhibitor, with an IC50 of 2.51 µM (20-times greater than that of BD2) . BRD4-BD1-IN-2 can be used in studies of cancer and cardiovascular diseases[1].
Product Specifications
CAS Number
2761321-26-8
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/brd4-bd1-in-2.html
Solubility
10 mM in DMSO
Smiles
CN1C(N(C(C2=C1N=C(N2CC3=CC=C(C=C3)Br)Br)=O)CC4=CC=C(C=C4)Br)=O
Molecular Formula
C20H15Br3N4O2
Molecular Weight
583.07
References & Citations
[1]Chang Y, et al. Design, synthesis, biological evaluation, and molecular docking of 1, 7-dibenzyl-substituted theophylline derivatives as novel BRD4-BD1-selective inhibitors. Medicinal Chemistry Research, 2021, 30 (8) : 1453-1468.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Available Sizes
Frequently Asked Questions
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