SphK1-IN-1
Product Specifications
UNSPSC Description
SphK1-IN-1 (compound 48) is a SphK1 inhibitor with effective antitumor activity. SphK1-IN-1 inhibits SphK1 ATPase with an IC50 value of 4.02 μM. SphK1-IN-1 can be used for the research of cancer[1].
Target Antigen
SphK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sphk1-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=NN(C(N2CCCCC2)=C1C3=NC4=CC([N+]([O-])=O)=CC=C4N3)C5=CC=CC=C5
Molecular Weight
402.45
References & Citations
[1]A. Galal, et al. Design and synthesis of new pyrazolylbenzimidazoles as sphingosine kinase-1 inhibitors. (2021) 1614–1634.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143296/SphK1-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143296/
Clinical Information
No Development Reported
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