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Pim-1 kinase inhibitor 1

Pim-1 kinase inhibitor 1 is a Pim-1 kinase inhibitor with an IC50 of 0.11 μM for Pim-1 kinase. Pim-1 kinase inhibitor 1 shows anticancer activity to several cancer cell lines by promotes cell apoptosis. Pim-1 kinase inhibitor 1 can be used for the research of cancer[1].

Product Specifications

CAS Number

[2803505-57-7]

UNSPSC

12352005

Target

Apoptosis; Pim

Type

Reference compound

Related Pathways

Apoptosis; JAK/STAT Signaling

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pim-1-kinase-inhibitor-1.html

Solubility

10 mM in DMSO

Smiles

N#C/C(C(NC1=CC=C(C=C1)O)=O)=C\C2=CC3=CC=CC=C3N=C2O

Molecular Formula

C19H13N3O3

Molecular Weight

331.32

References & Citations

[1]A. Ammar, et al. Carboxamide appended quinoline moieties as potential anti-proliferative agents, apoptotic inducers and Pim-1 kinase inhibitors. 2021.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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