Pim-1 kinase inhibitor 1
Pim-1 kinase inhibitor 1 is a Pim-1 kinase inhibitor with an IC50 of 0.11 μM for Pim-1 kinase. Pim-1 kinase inhibitor 1 shows anticancer activity to several cancer cell lines by promotes cell apoptosis. Pim-1 kinase inhibitor 1 can be used for the research of cancer[1].
Product Specifications
CAS Number
[2803505-57-7]
UNSPSC
12352005
Target
Apoptosis; Pim
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-1-kinase-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
N#C/C(C(NC1=CC=C(C=C1)O)=O)=C\C2=CC3=CC=CC=C3N=C2O
Molecular Formula
C19H13N3O3
Molecular Weight
331.32
References & Citations
[1]A. Ammar, et al. Carboxamide appended quinoline moieties as potential anti-proliferative agents, apoptotic inducers and Pim-1 kinase inhibitors. 2021.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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