Antibacterial agent 118

Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-118.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NC=CN=C1NC([C@]2(CC3C4)C[C@@H]4CC(C3)C2)=O)NC5=NC=CS5

Molecular Formula

C19H21N5O2S

Molecular Weight

383.47

References & Citations

[1]Juhás M, et al. Design, synthesis and biological evaluation of substituted 3-amino-N- (thiazol-2-yl) pyrazine-2-carboxamides as inhibitors of mycobacterial methionine aminopeptidase 1. Bioorg Chem. 2022 Jan;118:105489.