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NTPDase-IN-3

Product Specifications

UNSPSC Description

NTPDase-IN-3 (Compound 5e) is a NTPDase inhibitor, with IC50 values of: 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). NTPDase-IN-3 can be used in the research of cancers and thrombosis[1].

Target Antigen

NTPDase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ntpdase-in-3.html

Solubility

10 mM in DMSO

Smiles

CC(CC1=CC=C(C=C1)C(C(NC2=NN=C(S2)SCC3=CC=C(C=C3)Cl)=O)C)C

Molecular Weight

446.03

References & Citations

[1]Sadia Abbas, et al. Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors. Bioorg Chem. 2022 Jan;118:105456.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-143289/NTPDase-IN-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-143289/

Clinical Information

No Development Reported

CAS Number

2883147-45-1

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