NTPDase-IN-3
NTPDase-IN-3 (Compound 5e) is a NTPDase inhibitor, with IC50 values of: 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2) . NTPDase-IN-3 can be used in the research of cancers and thrombosis[1].
Product Specifications
CAS Number
[2883147-45-1]
UNSPSC
12352005
Target
NTPDase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ntpdase-in-3.html
Solubility
10 mM in DMSO
Smiles
CC(CC1=CC=C(C=C1)C(C(NC2=NN=C(S2)SCC3=CC=C(C=C3)Cl)=O)C)C
Molecular Formula
C22H24ClN3OS2
Molecular Weight
446.03
References & Citations
[1]Sadia Abbas, et al. Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors. Bioorg Chem. 2022 Jan;118:105456.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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