Topoisomerase II inhibitor 5
Selected Variant
HY-143281
Size: 1 Each
Topoisomerase II inhibitor 5 (Compound E24) is a DNA topoisomerase II inhibitor with anticancer activities[1].
Product Specifications
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-ii-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C([N+]([O-])=O)=CC=C2NC3=CC=C(CCN4CCN(C)CC4)C=C3)NC5=C1C=C(O)C=C5
Molecular Formula
C26H27N5O4
Molecular Weight
473.52
References & Citations
[1]Chen JN, et al. Structure-activity relationship of novel acridone derivatives as antiproliferative agents. Bioorg Med Chem. 2021 Jan 1;29:115868.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
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