HPA-IN-2
Product Specifications
UNSPSC Description
HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively[1].
Target Antigen
Amylases; Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hpa-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CN(N=N1)CCCCCCO[C@@H]2CC3=CC(O)=CC(O)=C3O[C@@H]2C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
Molecular Weight
648.66
References & Citations
[1]Chen W, et al. Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives. Bioorg Chem. 2022 Feb;119:105515.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143269/HPA-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143269/
Clinical Information
No Development Reported
CAS Number
2885971-91-3
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