HPA-IN-2
HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively[1].
Product Specifications
CAS Number
2885971-91-3
UNSPSC
12352005
Target
Amylases; Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hpa-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CN(N=N1)CCCCCCO[C@@H]2CC3=CC(O)=CC(O)=C3O[C@@H]2C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
Molecular Formula
C33H36N4O10
Molecular Weight
648.66
References & Citations
[1]Chen W, et al. Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives. Bioorg Chem. 2022 Feb;119:105515.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15385886 1 Vial
Lentiviral human APOBR sgRNA gene knockout kit - Lentiviral human APOBR sgRNA gene knockout kit (plasmid)
Sign In for Pricing
View Details 
ARP49643_P050 100 µL
SRPRB antibody - middle region (ARP49643_P050)
Sign In for Pricing
View Details GTR15172882 1 Vial
Lentiviral mouse Serpinb9f shRNA (UAS) - Lentiviral mouse Serpinb9f shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details 
bs-2526R-BF594 100 µL
CD160 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Sign In for Pricing
View Details